Likely to be an impossible project:
Get people to take a snapshot of an object/view of concentration or unconscious stare directly before and after a gender reassignment (or related) surgery. I would then translate those photographs into small (11x14) drawings or paintings. The final pieces would be diptychs, or possibly triptychs including the patient's self-portrait.
(This was a very quick thought. Still working on it, even though it probably will never be executed.)